TSH Receptor Antibody (TRAb)
TBII, Thyrotropin Binding Inhibiting Immunoglobulins, Thyroid Stimulating, ARUP #2002734, EPIC: LAB6172, SOFT: XTRAB
Specimen Collection Criteria
Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.
Physician Office/Drawsite Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and freeze (-20°C/-4°F or below).
Preparation for Courier Transport
Transport: 1.0 mL serum, frozen (-20°C/-4°F or below). (Min: 0.3 mL)
- Lipemic specimens.
- Grossly hemolyzed specimens.
- Specimens not collected and processed as indicated.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 72 hours
Frozen (-20°C/-4°F or below): 1 month
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.
Sent to ARUP Laboratories, Salt Lake City, UT.
Sunday - Saturday.
Results available in 2-4 days.
Less than or equal to 1.75 IU/L.
Quantitative Electrochemiluminescent Immunoassay.
- TSH Receptor Antibodies are measured in this assay by the thyrotropin binding inhibiting immunoglobulin technique (TBII). Results are reported as percent inhibition of TSH binding.
- Positive results are consistent with autoimmune thyroid disease.
The TSH receptor antibody (TRAb) assay aids in the differential diagnosis of Graves' disease (positive in > 85%) versus toxic nodular goiter. TRAb levels aid the clinician in prescribing the most appropriate course of therapy upon initial diagnosis. This assay is also used to monitor the efficacy of anti-thyroid drug therapy to predict the likelihood of disease remission.
ARUP #2002734, EPIC: LAB6172, SOFT: XTRAB
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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills,
Grosse Pointe, Royal Oak, and Troy campuses.