Vitamin E Level
Alpha-tocopherol Levels, Vitamin E, Serum, MAYO: VITE, EPIC: LAB6182, SOFT: XVITE
- The patient must be fasting 12-14 hours prior to specimen collection (for infants, collect specimen just prior to next schedule feeding).
Specimen Collection Criteria
Collect: One plain Red-top tube.
Also acceptable: One Gold-top SST tube.
Physician Office/Drawsite Specimen Preparation
Protect specimen from light. Let specimen clot 30-60 minutes and immediately centrifuge to separate serum from cells. Transfer serum to an amber plastic transport tube and refrigerate (2-8°C or 36-46°F).
Preparation for Courier Transport
Transport: 0.5 mL light-protected serum, refrigerated (2-8°C or 36-46°F). (Min: 0.25 mL)
- Hemolyzed specimens.
- Lipemic specimens.
- Specimens not collected and processed as indicated.
- Specimens not protected from light.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 14 days
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.
Sent to Mayo Medical Laboratories, Rochester, MN.
Monday - Friday.
Results available in 3-6 days.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Specific quantitation of alpha-tocopherol.
Serum vitamin E concentrations are correlated with serum lipids, and accurate assessment may require calculation of a lipid ratio.
Significant deficiency of vitamin E (less than 3.0 mg/L) is associated with improper specimen collection and malabsorption syndromes. Significant excess (greater than 40 mg/L) is often associated with hyperlipidemia.
This assay is used to evaluate vitamin E deficiency in hemolytic disease in premature infants, and neuromuscular disease in infants (and adults) with chronic cholestasis. It is also used to evaluate patients on long-term parenteral nutrition, patients with malignancy or malabsorption, and to investigate brown-bowel syndrome. Infertility in both males and females may be a manifestation of vitamin E deficiency. Vitamin E has been used for the treatment of habitual abortion and sterility. There has been no conclusive evidence that vitamin E has any beneficial effect on these conditions. High doses of vitamin E appear to be tolerated without significant adverse effects.
MAYO: VITE, EPIC: LAB6182, SOFT: XVITE
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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills,
Grosse Pointe, Royal Oak, and Troy campuses.