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Beaumont Laboratory

Mexiletine

Mexitil®, ARUP #2011539, EPIC: LAB6105, SOFT: XMEX

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.

Time of Collection: Trough, just prior to the next dose.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Serum Separator (SST) tubes.
  • Specimens not collected or processed as indicated.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 5 days
Frozen (-20°C/-4°F or below): 2 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Tuesday, Thursday, Saturday.
Results available in 2-6 days.

Reference Range

Therapeutic: 1.0-2.0 mcg/mL.
Toxic: Greater than 2.0 mcg/mL. 

Test Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Mexiletine is indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that in the judgement of the physician, are life-threatening. This assay is used for the therapeutic monitoring and toxicity assessment of mexiletine.

CPT Code

80299.

Test Codes

ARUP #2011539, EPIC: LAB6105, SOFT: XMEX

Last Updated

12/12/2016

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.