Homovanillic Acid (HVA), Urine
HVA, Urine Homovanillic Acid , Homovanillic Acid, Urine, ARUP #80422, EPIC: LAB7061, SOFT: XHVA
- A Urine Creatinine test is performed on each sample.
- Please refer to the Specimen Collection Manual for instructions on 24 Hour Urine Collection:
Specimen Collection Criteria
Collect (preferred specimen): 24 hour urine with no preservatives.
Also acceptable: Random urine specimen in a screw-capped container (preferred) or other sterile collection cup. (Min: 1.0 mL)
- Keep 24 hour urine specimen iced or refrigerated during collection.
- Include start and end dates and times for the collection period on the specimen container.
- The specimen must be transported to the Laboratory immediately after the end of the collection interval.
Urine Preservative Options
6N Hydrochloric Acid
Boric Acid (10g)
50% Acetic Acid
Physician Office/Drawsite Specimen Preparation
Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.
Preparation for Courier Transport
Transport: Entire 24 hour urine collection or random urine, refrigerated (2-8°C or 36-46°F).
- Samples not kept refrigerated (2-8°C or 36-46°F).
- Specimens not collected and processed as indicated.
Specimen Stability for Testing:
Room temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (with preservative) (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 14 days
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.
Sent to ARUP Laboratories, Salt Lake City, UT.
Tuesday - Saturday.
Results available in 3-6 days.
Quantitative High-Performance Liquid Chromatography (HPLC) - Tandem Mass Spectrometry.
HVA is the primary metabolite of dopamine and elevations reflect increased dopamine levels due to either a tumor or drug therapy. Levels can be extremely elevated in urines from patients receiving dopamine, L-dopa, disulfiram and reserpine.
This assay is helpful in the diagnosis of pheochromocytoma, neuroblastoma, or ganglio-blastoma and to monitor the patient's response to therapy. If neuroblastoma is suspected, it is best to determine Vanillylmandelic Acid (VMA), Urine levels since either dopamine or norepinephrine could be increased.
ARUP #80422, EPIC: LAB7061, SOFT: XHVA
Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.
This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills,
Grosse Pointe, Royal Oak, and Troy campuses.