Beaumont Laboratory - Lab Test Details

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Beaumont Laboratory

Immunoglobulin G (IgG)

IgG , Immunoglobulin G, Serum, Antrim #30435, EPIC: LAB5786, SOFT: IGG

Specimen Collection Criteria

Collect: One Gold-top SST tube. (Minimum Whole Blood: 4.0 mL)

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged collection tube within 12 hours of collection. (Minimum Serum: 0.5 mL)

Preparation for Courier Transport

Transport: Centrifuged collection tube, refrigerated (2-8°C or 36-46°F). (Minimum Serum: 0.5 mL)

Rejection Criteria

  • Grossly lipemic specimens.
  • Hemolyzed specimens.
  • Plasma specimens.


Specimen Stability for Testing:

Centrifuged SST tubes, Red-top tubes, and Microtainers®
Room Temperature (20-26°C or 68-78.8°F): 12 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 12 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days


Royal Oak Automated Chemistry Laboratory.


Sunday - Saturday.
Results available within 24 hours of receipt in the Laboratory.

Reference Range

0-29 Days: 552-1443 mg/dL
1-3 Months: 157-592 mg/dL
4-6 Months: 100-474 mg/dL
7-12 Months: 264-822 mg/dL
13-24 Months: 138-901 mg/dL
25-36 Months: 438-1091 mg/dL
3-5 Years: 480-1284 mg/dL
6-8 Years: 627-1376 mg/dL
9-11 Years: 701-1452 mg/dL
12-16 Years: 635-1410 mg/dL
Adult Range: 520-1560 mg/dL

Test Methodology



Decreased levels of IgG are associated with selective hypo-IgG, protein losing enteropathies, pregnancy, and nephrotic syndrome.

Increased IgG levels are associated with infectious diseases (hepatitis, rubella, infectious mononucleosis), parasitic diseases, rheumatoid arthritis, systemic lupus erythematosus, polyclonal and monoclonal gammopathies, multiple myeloma, monocytic leukemia, and Hodgkin's disease.

Half Life in Blood: 21 days.

Clinical Utility

IgG levels can be used to evaluate humoral immunity and aids in the diagnosis of conditions associated with IgG excess or depression. IgG can cross the placenta. IgG antibodies are the most important and persistent antibodies of the secondary immune response.

CPT Code


Test Codes

Antrim #30435, EPIC: LAB5786, SOFT: IGG

Last Updated


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UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.