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Beaumont Laboratory

Serotonin Release Assay

SRA., Blood Center of Wisconsin: BCW5508, EPIC: LAB6506, SOFT: XSRA


This test is now ordered automatically on patients with a Heparin Platelet Factor 4 Antibody OD of 0.4 to 1.999. The SRA should only be ordered directly when there is a very strong clinical suspicion of heparin induced thrombocytopenia. In such cases, the ordering physician will need approval from a pathologist or pathology resident. Contact the Laboratory at 800-551-0488 with any questions.

Specimen Collection Criteria

Collect: Two plain Red-top tubes.

Send specimens to the Laboratory immediately after collection for processing. 

Physician Office/Drawsite Specimen Preparation

Let specimens clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tubes and refrigerate (2-8°C or 36-46°F) immediately.

Preparation for Courier Transport

Transport: 5.0 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 1.0 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Undetermined
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 60 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.


Sent to Blood Center of Wisconsin, Milwaukee, WI.


Monday - Saturday.
Results available in 2-5 days.

Reference Range


Test Methodology

C-Serotonin Release Assay.

CPT Code


Test Codes

Blood Center of Wisconsin: BCW5508, EPIC: LAB6506, SOFT: XSRA

Last Updated


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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.