Antivirogram™, HIV Phenotype Resistance Testing , MONOGRAM #V3200, Testing requires pathology approval prior to collection.
This test is not included in the Beaumont Laboratory testing formulary, however, the Laboratory can facilitate specimen collection.
- This test requires pathology review. Contact the Sendout Laboratory at 248-551-9045 before ordering this test.
- Testing requires the ordering physician to complete forms for the independent clinical laboratory performing the testing.
- This test will be billed to the patient's insurance. If not covered by insurance, the patient is responsible for the full cost of testing.
- Specimens received without the appropriate forms and information will not be shipped.
- Once approved, order test as a Miscellaneous Sendout (XMISC).
Specimen Collection Criteria
Collect: Three Lavender-top EDTA tubes, after obtaining necessary pathology approval.
Physician Office/Drawsite Specimen Preparation
Centrifuge to separate plasma from cells within six hours of collection. Transfer plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.
Preparation for Courier Transport
Transport: 4.0 mL plasma, frozen (-20°C/-4°F or below). (Min: 3.0 mL)
- Specimens received without prior Laboratory notification and review.
- Hemolyzed specimens.
- Specimens not collected and processed as indicated.
Monday - Saturday.
Results available within one month.
Polymerase Chain Reaction (PCR) Amplification and Viral Culture.
- Phenotyping is the actual measurement of viral resistance found by growing the virus derived from each patient in the presence of antiviral drugs.
- Limitations: This procedure may not be successful when the viral load is less than 500 copies per milliliter of plasma. If there is insufficient virus to produce results, HIV-1 RNA quantitation will be performed to confirm viral load.
This assay detects resistance in HIV-1 to antiretroviral drugs.
- Roos MTL, Lange JMA, deGoede REY. Viral phenotype and immune response in primary human immunodeficiency virus type 1 infection. J Infect Dis 1992; 165:427-32.
MONOGRAM #V3200, Testing requires pathology approval prior to collection.