Details

Hepatitis E Ab, IgG

Hepatitis E IgG, Hepatitis E Antibody, IgG , ARUP #2010151, EPIC: LAB6621, SOFT: XHPEG

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube or one Lavender-top EDTA tube.

Send specimen for processing immediately after collection. 

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.3 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.

Storage

Ambient: 2 weeks
Refrigerated: 2 months

Performed

Tuesday, Friday.
Results available in 2-9 days.

Reference Range

By report.

Test Methodology

Qualitative Enzyme-Linked Immunosorbent Assay (ELISA).

Interpretation

Both IgM and IgG antibody to HEV (anti-HEV) are elicited following HEV infection. The titer of IgM anti-HEV declines rapidly during early convalescence. IgG anti-HEV persists and appears to provide at least short-term protection against disease.

Clinical Utility

This test is used for the in vitro detection of IgG and IgM antibodies to hepatitis E virus in human serum.

Clinical Disease

The epidemiology and clinical course of viral hepatitis E are similar to that of hepatitis A. There is no evidence of a chronic form. The case fatality rate is similar to that of hepatitis A, except in pregnant women where the rate may reach 20% during the third trimester of pregnancy.

Reference

  1. Benenson, Abram. Control of Communicable Diseases in Man, 15th edition, American Public Health Association, Washington, DC. 1990.

CPT Code

86790.

Test Codes

ARUP #2010151, EPIC: LAB6621, SOFT: XHPEG

Last Updated

7/11/2019