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Ribosomal P Protein Antibody

Test Codes

EPIC: LAB6145, Beaker: XRIBP, Mayo: RIB

Department

Special Chemistry

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.4 mL)

Rejection Criteria

• Grossly lipemic specimens.
• Grossly hemolyzed specimens
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.4 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): unacceptable
Refrigerated (2-8°C or 36-46°F): 21 days
Frozen (-20°C/-4°F or below): 21 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Special Chemistry Laboratory Royal Oak

Performed

Monday – Saturday.
Results available in 1-3 days.

Reference Range

By report.

Test Methodology

Multiplex Flow Immunoassay.

Clinical Utility

Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus (SLE). Ribosomal P Antibodies are found in approximately 12% of patients with SLE and in 90% of patients with lupus psychosis; titers often increase more than five-fold during and before active phases of psychosis.

CPT Codes

83516

Contacts

Last Updated

3/14/2024