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JC Polyoma Virus DNA PCR, Qualitative

JC Virus (JCV) DNA Detection, JC Polyoma Virus DNA, Real-Time PCR

Test Codes

EPIC: LAB7567, Beaker: XJCQUAL, ARUP: 0099169

Department

Send Outs

Specimen Collection Criteria

Collect: One of the following specimen types:

• Blood: One Lavender-top EDTA tube or Gold-top SST tube
• Cerebrospinal Fluid: 1 mL CSF in a sterile collection container. (Minimum: 0.5 mL)
• Urine: 1 mL urine in a sterile collection container. (Minimum: 0.5 mL)

Physician Office/Draw Specimen Preparation

Centrifuge blood specimens to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately. Maintain CSF and urine specimens frozen (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: 1 mL serum, plasma, CSF, or urine, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Rejection Criteria

Specimens not collected or processed as indicated.

In-Lab Processing

Centrifuge blood specimens to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately. Maintain CSF and urine specimens frozen (-20°C/-4°F or below) prior to transport.

Transport: 1 mL serum, plasma, CSF, or urine, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 5 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratory in Salt Lake City, UT.

Performed

Monday, Wednesday, Friday.
Results available in 3-5 days. 

Reference Range

By report.

Test Methodology

Qualitative Polymerase Chain Reaction

Interpretation

By report.

Clinical Utility

The detection of JCV can aid in the diagnosis of progressive multifocal leukoencephalopathy (PML), a viral infection that infects the human central nervous system. JCV is usually associated with immunosuppression of the cell-mediated immune system in patients with lymphoreticular malignant disease, organ transplantation, and acquired immunodeficiency syndrome.

CPT Codes

87798

Contacts

Last Updated

9/18/2023