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Acetazolamide Level (Southeast Michigan Only)

Diamox, Dazamide, Storzolamide

Test Codes

EPIC: LAB1231182, Beaker: XACET, ARUP: 91366

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to the next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Rejection Criteria

• Serum Separator (SST) Tubes.
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL) 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 1 month
Refrigerated (2-8°C or 36-46°F): 1 month
Frozen (-20°C/-4°F or below): 1 month

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Varies.
Results available in 5-8 days.

Reference Range

By report.

Test Methodology

Quantitative High-Performance Liquid Chromatography – Tandem Mass Spectrometer.

Interpretation

By report.

Clinical Utility

Acetazolamide is a potent inhibitor of carbonic anhydrase. It is used in the treatment of glaucoma, mountain sickness (e.g., headache, nausea, dizziness, drowsiness, fatigue, and shortness of breath), and as an antiepileptic and diuretic. This assay is used for the therapeutic monitoring and toxicity assessment of Acetazolamide.

CPT Codes

80375 (alternate code: G0480).

Contacts

Last Updated

10/25/2024