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Thioridazine/Mesoridazine

Mellaril^®

Test Codes

NMS: 4461SP, Order as a Miscellaneous Send Out.

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to the next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.7 mL)

Rejection Criteria

• Serum Separator (SST) tubes.
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.7 mL) 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 days
Refrigerated (2-8°C or 36-46°F): 8 days
Frozen (-20°C/-4°F or below): 12 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Tuesday, Thursday.
Results available in 4-10 days.

Reference Range

By report.

Test Methodology

Gas Chromatography.

Interpretation

Chronic high therapeutic concentrations for total drug may reach 7 mcg/mL. Toxic range is not well defined. Some patients may show toxicity at therapeutic concentrations.

Clinical Utility

Thioridazine is indicated for the management of manifestations of psychotic disorders. This assay is used to monitor the therapeutic drug level and to evaluate toxicity of thioridazine.

CPT Codes

80342

Contacts

Last Updated

10/3/2023