Salicylate, Blood Level
Aspirin, Salicylate Level, Serum
Test Codes
EPIC: LAB34, SALIC, Antrim #15980
Department
Chemistry
Specimen Collection Criteria
Collect: One plain Red-top tube. (Minimum Whole Blood: 1.0 mL)
Do not use Serum Separator Tubes.
Record the exact time of specimen collection on the tube or in the computer system.
Physician Office/Draw Specimen Preparation
Let specimens clot 30-60 minutes and refrigerate (2-8°C or 36-46°F) the collection tube within two hours of collection. (Minimum: 1.0 mL blood)
Preparation for Courier Transport
Transport: Collection tube, refrigerated (2-8°C or 36-46°F). (Minimum: 1.0 mL blood)
Rejection Criteria
- Serum Separator (SST) tubes.
- Severely lipemic or hemolyzed specimens.
In-Lab Processing
Let specimens clot 30-60 minutes. Centrifuge specimen to separate serum from cells. Deliver an aliquot of serum or the collection tube immediately to the appropriate testing station.
Storage
Specimen Stability for Testing:
Collection Tubes
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable
Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months
Specimen Storage in Department Prior to Disposal:
Refrigerated (2-8°C or 36-46°F): 7 days
Laboratory
Canton Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Lenox Main Laboratory
Livonia Main Laboratory
Royal Oak STAT Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Troy Chemistry Laboratory
Wayne Chemistry Laboratory
Performed
Sunday – Saturday, 24 hours a day.
STAT results available within 1 hour of receipt in the Laboratory.
Routine results available within 24 hours.
Reference Range
Therapeutic Range: 0-25 mg/dL.
Critical Range: Greater than 30 mg/dL.
Test Methodology
Enzyme/Colorometric.
Interpretation
Chronic low dose salicylate dosing results in a therapeutic level of approximately 6 mg/dL and monitoring is not required. In rheumatoid arthritis therapy, large doses of salicylate are administered and monitoring serum levels is desirable to maintain a therapeutic range of 15-30 mg/dL.
Clinical Utility
The salicylate assay aids in the diagnosis and treatment of salicylate overdose and in monitoring salicylate levels to insure appropriate therapy. Salicylates are a group of compounds used as analgesics, antipyretics and anti-inflammatory agents. Acetylsalicylic acid (aspirin) is the most commonly used salicylate. Salicylates are readily available over-the-counter and most salicylate therapy is the result of patient self-medication. For this reason, salicylates are often seen in overdose cases. Salicylate poisoning is seldom fatal, but causes side effects ranging from nausea, vomiting and tinnitus to fever, lethargy and coma. Prompt recognition and management are necessary to avoid serious consequences.
CPT Codes
80329 (alternate: G0480).
LOINC: 4024-6
Contacts
Livonia Laboratory – LVA
947-523-4370
Name: Livonia Laboratory – LVA
Location:
Phone: 947-523-4370
STAT Laboratory – RO
248-898-0325
Name: STAT Laboratory – RO
Location:
Phone: 248-898-0325
Lenox Laboratory – LNX
947-523-4070
Name: Lenox Laboratory – LNX
Location:
Phone: 947-523-4070
Chemistry Laboratory – TRN
734-671-3165
Name: Chemistry Laboratory – TRN
Location:
Phone: 734-671-3165
Chemistry Laboratory – DBN
313-436-2196
Name: Chemistry Laboratory – DBN
Location:
Phone: 313-436-2196
Chemistry Laboratory – TYL
313-295-5360
Name: Chemistry Laboratory – TYL
Location:
Phone: 313-295-5360
Main Laboratory –WYN
734-467-4274
Name: Main Laboratory –WYN
Location:
Phone: 734-467-4274
Canton Laboratory – CTN
734-454-8024
Name: Canton Laboratory – CTN
Location:
Phone: 734-454-8024
Chemistry Laboratory – FH
947-521-5252
Name: Chemistry Laboratory – FH
Location:
Phone: 947-521-5252
Chemistry Laboratory – GP
313-473-1807
Name: Chemistry Laboratory – GP
Location:
Phone: 313-473-1807
Chemistry Laboratory – TR
248-964-8070
Name: Chemistry Laboratory – TR
Location:
Phone: 248-964-8070
Last Updated
11/19/2024
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