Lab Test

Porphobilinogen, 24 Hour Urine Quantitative

Instructions

Specimen Collection Criteria

Collect (preferred specimen): 24 hour urine sample with no preservative.
Also acceptable: Random urine specimen in a screw-capped container (preferred) or other sterile collection cup. (Minimum: 2.0 mL)

  • Keep 24 hour urine specimen iced or refrigerated during collection.
  • Include start and end dates and times for the collection period on the specimen container.
  • All specimens must be protected from light.
Urine Preservative Options
No Preservative
6N Hydrochloric Acid
Boric Acid (10g)
Sodium Carbonate
50% Acetic Acid
REQUIRED
Unacceptable
Unacceptable
Unacceptable
Unacceptable

Physician Office/Draw Specimen Preparation

Protect specimen from light. Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: Entire 24 hour urine collection, or random urine, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

  • Specimens not collected and processed as indicated. 

In-Lab Processing

Protect specimen from light. Measure total volume of 24 hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot two 4.0 mL aliquots from the well-mixed 24 hour urine collection or random urine into amber transport tubes and freeze (-20°C/-4°F or below). (Minimum: 3.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 4 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday – Friday.
Results available in 2-5 days.

Reference Range

By report.

Test Methodology

Quantitative Ion Exchange Chromatography/Spectrophotometry.

Interpretation

By report.

Clinical Utility

This test is used to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.

CPT Codes

84110

Contacts

Last Updated

10/23/2019

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

 

This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.