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Porphobilinogen, 24-Hour Urine Quantitative

Test Codes

EPIC: LAB1231235, Beaker: XPBGU, ARUP: 80260

Department

Send Outs

Instructions

• A Urine Creatinine is included with this test.
• Please refer to the Specimen Collection Manual for instructions on 24-Hour Urine Collection:
• Urine 24-Hour Collection - Inpatient
• Urine 24-Hour Collection - Outpatient
• Urine 24-Hour Collection - Outreach

Specimen Collection Criteria

Collect (preferred specimen): 24-hour urine sample with no preservative.
Also acceptable: Random urine specimen 2.0 mL in a screw-capped container (preferred) or other sterile collection cup. (Minimum: 1.5 mL)

• Keep 24-hour urine specimen iced or refrigerated during collection.
• Include start and end dates and times for the collection period on the specimen container.
• All specimens must be protected from light.

Urine Preservative Options
No Preservative	6N Hydrochloric Acid	Boric Acid (10g)	Sodium Carbonate	50% Acetic Acid
REQUIRED	Unacceptable	Unacceptable	Unacceptable	Unacceptable

Physician Office/Draw Specimen Preparation

Protect specimen from light. Maintain specimens frozen (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: Entire 24-hour urine collection, or random urine, frozen (-20°C/-4°F or below).

Rejection Criteria

Specimens not collected and processed as indicated. 

In-Lab Processing

Protect specimen from light. Measure total volume of 24-hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot two 4.0 mL aliquots from the well-mixed 24-hour urine collection or random urine into amber transport tubes and freeze (-20°C/-4°F or below). (Minimum: 1.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 4 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Sunday – Saturday.
Results available in 1-5 days.

Reference Range

By report.

Test Methodology

Quantitative Ion Exchange Chromatography / Spectrophotometry.

Interpretation

By report.

Clinical Utility

This test is used to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.

CPT Codes

84110

Contacts

Last Updated

9/18/2024