Lab Test

Polymyositis (PM-1) Antibody (Southeast Michigan Only)

PM-Scl antibody, PM-1 Antibody, PM/Scl-100 Antibody, IgG

Test Codes

EPIC: LAB1231217, Beaker: XPM1A, ARUP: 2003040

Department

Send Outs

Specimen Collection Criteria

Collect: One plain Red-top tube.

Also acceptable: One Gold-top SST tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Rejection Criteria

Specimens not collected and processed as indicated.  

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 2 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Tuesday, Thursday, Saturday.
Results available in 2-5 days.

Reference Range

Negative.

Test Methodology

Qualitative Immunoblot.

Interpretation

By report.

Clinical Utility

PM-Scl antibody is detected in over 90% of patients with polymyositis and scleroderma (Scl) overlap syndrome, but only in about 8% of all myositis patients and only 3% of all scleroderma patients.

CPT Codes

86235

Contacts

Last Updated

11/12/2024

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