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Opiate Confirmation, Urine

Test Codes

EPIC: LAB6922, OPTCF

Department

Toxicology

Specimen Collection Criteria

Collect: 50 mL random urine in a screw-capped container (preferred) or other sterile collection cup with no preservative. (Minimum: 30 mL)

• Refrigerate the specimen immediately after collection.
• Record the exact time of specimen collection on the container or in the computer system.

Preparation for Courier Transport

Transport: 50 mL urine, refrigerated (2-8°C or 36-46°F). (Minimum: 30 mL)

Rejection Criteria

• Specimens not collected and processed as indicated.
• Urine Vacutainer^® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts. 

In-Lab Processing

Analyze specimen immediately upon receipt in the Laboratory.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Toxicology Laboratory, Royal Oak 

Performed

Sunday – Saturday, results available within 3-5 business days. 

Test Methodology

Liquid Chromatography/ Tandem Mass Spectrometer (LC/MS/MS).

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Interpretation

Drugs identified: Codeine, Morphine, Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone, 6-Acetylmorphine.

Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure.

Clinical Utility

Opiates act on several sites of the central nervous system. Their use results in analgesia, drowsiness, mood changes and some mental clouding. This assay is used to aid in the diagnosis and treatment of opiate use or abuse. 

CPT Codes

80365
LOINC: 19295-5, 8219-8, Codeine 16197-6, Morphine 16196-8, Hydrocodone 19483-7, Hydromorphone 18473-9, Oxycodone 19643-6, Oxymorphone 18325-1

Contacts

Last Updated

4/14/2023