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Myoglobin, Qualitative Urine

Myoglobin Screen, Urine

Test Codes

EPIC: LAB5914, Beaker: MYOU

Department

Chemistry

Specimen Collection Criteria

Collect: A random, clean-catch, midstream urine specimen in a screw-capped container (preferred) or other sterile collection container. (Minimum: 5.0 mL)

• A fairly concentrated (first morning void) specimen is preferred.
• Optimum specimen volume is at least 20 mL.
• Document the time of the specimen collection.
• Please refer to the Specimen Collection Manual for instructions on Random Urine Collection:
  • Random Urine Collection

Physician Office/Draw Specimen Preparation

Refrigerate (2-8°C or 36-46°F) the specimen immediately after collection and arrange for transportation to the Laboratory. Maintain refrigerated prior to transport. (Minimum: 5.0 mL)

Preparation for Courier Transport

Transport: Urine in a sterile collection container, refrigerated (2-8°C or 36-46°F). (Minimum: 5.0 mL)

Rejection Criteria

Specimens not collected and processed as indicated. 

In-Lab Processing

Immediately upon receipt in the Laboratory, the specimen will be screened for Hemoglobin. If positive, an aliquot will be pH adjusted and sent to Royal Oak Urinalysis to complete testing.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 1 hour
Refrigerated (2-8°C or 36-46°F): 72 hours
Frozen (-20°C/-4°F or below): 1 month

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Grosse Pointe Hematology/Urinalysis Laboratory
Royal Oak Urinalysis Laboratory
Troy Hematology/Urinalysis Laboratory

Performed

Sunday – Saturday, 24 hours a day. 
STAT results available within 4 hours of receipt in the Laboratory.
Routine results available within 24 hours.

Reference Range

Negative.

Test Methodology

Manual – Qualitative, visual screen for hemoglobin (dipstick) after precipitation of interfering hemoglobin with ammonium sulfate.

Interpretation

The presence of myoglobin in the urine indicates recent muscle damage and may lead to renal tubular damage.

Clinical Utility

Severe injury to striated muscle tissue from crush injuries, high voltage electrical shock and occasionally severe muscle exertion, may cause myoglobinuria.

CPT Codes

83874

Contacts

Last Updated

10/30/2023