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Methadone Screen, Urine

Urine Methadone Screen

Test Codes

EPIC: LAB1230992, Beaker: MET9, Antrim: 17075

Department

Chemistry

Specimen Collection Criteria

Collect: 50.0 mL random urine in a screw-capped container (preferred) or other sterile collection cup. (Minimum: 30 mL)

• Refrigerate the specimen immediately after collection.
• Record the exact time of specimen collection on the container or in the computer system.

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 50.0 mL urine, refrigerated (2-8°C or 36-46°F). (Minimum: 30.0 mL)

Rejection Criteria

• Specimens not collected and processed as indicated.
• Urine Vacutainer^® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts.

In-Lab Processing

Analyze urine specimen immediately upon receipt in the Laboratory.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Frozen (-20°C/-4°F or below): 2 months

Laboratory

Canton Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Royal Oak Automated Chemistry Laboratory
Royal Oak Toxicology Laboratory
Troy Chemistry Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Wayne Chemistry Laboratory 

NOTE: Screens are performed at Canton, Dearborn, Farmington Hills, Grosse Pointe, Royal Oak, Taylor, Trenton, Troy, and Wayne. All confirmations are performed at Royal Oak. 

Performed

Sunday – Saturday, 24 hours a day.
STAT screen results available within 1 hour of receipt in the Laboratory, and confirmation within 12 hours.

Routine results available within 24 hours. 

Reference Range

None Detected (Positive Cutoff: 300 ng/mL).

Test Methodology

Screen: Enzyme Immunoassay.
Confirmation: Gas Liquid Chromatography/Mass Spectrometer (GC/MS).

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Interpretation

Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure.

Clinical Utility

Methadone is a synthetic narcotic analgesic that is similar to morphine. Methadone is commonly prescribed as the drug of choice in the maintenance treatment of heroin addicts. Patients in methadone therapy are routinely screened for methadone as a measure of compliance. This assay is used to aid in the diagnosis and treatment of methadone use or abuse. This assay provides a preliminary analytical result. Positive results are confirmed by chromatographic methods.

CPT Codes

80307, 80358 (alternate: G0479, G0480).

Contacts

Last Updated

7/21/2024