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Meprobamate

Equanil, Miltown, Meprospan, Neuramate, Equagesic

Test Codes

EPIC: LAB6096, Beaker: XMBAM, NMS: 2650SP

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to the next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.7 mL)

Rejection Criteria

Serum Separator (SST) tubes.

Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.7 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 21 days
Refrigerated (2-8°C or 36-46°F): 21 days
Frozen (-20°C/-4°F or below): 21 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to NMS lab, Horsham, PA.

Performed

Sunday, Tuesday Thursday.
Results available within 2-5 days.

Reference Range

Dose-Related Range: 5-20 mcg/mL.
Toxic: Greater than 40 mcg/mL.

Test Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Meprobamate is a propanediol carbamate sedative and tranquilizer, having pharmacological effects similar to barbiturates. This assay is used for the therapeutic monitoring and toxicity assessment of meprobamate.

CPT Codes

80369 (alternate: G0480).

Contacts

Last Updated

10/9/2023