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Islet Cell Antibody, IgG (Southeast Michigan Only)

Test Codes

EPIC: LAB1231484, Beaker: XICA, ARUP: 50138

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerate (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Rejection Criteria

• Hemolyzed specimens.
• Severely lipemic specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerate (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Sunday – Saturday.
Results available in 2-4 days.

Reference Range

Less than 1:4 - No antibody detected.

Test Methodology

Semi-Quantitative Indirect Fluorescent Antibody.

Interpretation

Islet cell antibodies have been associated with "autoimmune" endocrine disorders and insulin dependent diabetes. This disorder is characterized by the presence of antibodies in patients that may be detected years before the onset of the clinical symptoms.

To calculate JDF units: Multiply the titer x 5 (1:8 8 x 5 = 40 JDF Units).

Clinical Utility

This assay is used to aid in the diagnosis of "autoimmune" endocrine disorders and insulin dependent diabetes.

CPT Codes

86341

Contacts

Last Updated

11/1/2024