Lab Test

Iron, Liver Tissue

MAYO: FET, EPIC: LAB6293, SOFT: XFELT

Instructions

  • Contact the Laboratory at 248-551-9045 or 800-551-0488 prior to specimen procurement.
  • Suspected diagnosis and relevent clinical information must be included with the specimen.

Specimen Collection Criteria

Collect (preferred specimen): Liver tissue in a Mayo Medical Laboratories metal-free specimen vial. (Min: 2.0 mg)

  • Typically a piece of tissue from a 22-gauge needle biopsy at least 2.0 cm long.
  • If an 18-gauge needle is used, the tissue must be at least 1.0 cm in length. The 18-gauge needle produces a specimen that is thin and fragile and difficult to remove from paraffin.

Also acceptable: Liver tissue in a paraffin block.

  • Any specimen vial used other than a Mayo metal-free vial should be plastic, leached with 10% nitric acid for 48 hours, rinsed with redistilled water, and dried in clean air.
  • The following table provides the minimum specimen size requirements for tissue analysis.
Type of Biopsy Minimum Specimen Size
22 gauge needle 0.3 x 10-20 mm (about 2.0 cm in length)
18 gauge needle 1.0 x 5-10 mm (about 1.0 cm in length)
Wedge biopsy 10 mg

Physician Office/Drawsite Specimen Preparation

Maintain specimen in an appropriate container, refrigerated (2-8°C or 36-46°F), prior to transport.

Preparation for Courier Transport

Transport: Tissue specimen in a Mayo Medical Laboratories metal-free vial, or other appropriate container, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

  • Specimens not collected and processed as indicated.

Performed

Monday, Wednesday, Friday.
Results available in 3-6 days.

Reference Range

Iron:
Males: 200-2,400 mcg/g dry weight.
Females: 400-1,600 mcg/g dry weight.

Iron Index:
Less than 1.0 mcmol/g/year. Reference values have not been established for patients that are under 13 years old.

Test Methodology

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS).

Interpretation

By report.

Clinical Utility

This assay aids in the diagnosis of hemochromatosis.

CPT Code

83540.

Test Codes

MAYO: FET, EPIC: LAB6293, SOFT: XFELT

Last Updated

7/11/2019

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

 

This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.