Lab Test

IDH1 and IDH2 Mutation

U of M: IDH, EPIC: LAB7100, SOFT: XIDHG

Test Codes

U of M: IDH, EPIC: LAB7100, SOFT: XIDHG

Specimen Collection Criteria

Collect (preferred specimen): Blood in one Lavender-top EDTA or Yellow-top ACD tube. (Minimum: 1.0 mL)
Also acceptable: Bone marrow aspirate in one Lavender-top EDTA or Yellow-top ACD tube (Minimum: 0.5 mL) or Extracted DNA(50 ng/mcL).

Invert several times to mix blood or bone marrow.

Physician Office/Draw Specimen Preparation

Do not centrifuge. Maintain specimen in original collection tube, refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 5.0 mL blood or 2.0 mL bone marrow, refrigerated (2-8°C or 36-46°F) in original collection tube. (Minimum: 1.0 mL blood or 0.5 mL bone marrow).

Rejection Criteria

  • Frozen specimens.
  • Centrifuged specimens.
  • Specimens in clot or SST tubes.
  • Specimens not collected and processed as indicated.

In-Lab Processing

Do not centrifuge. Maintain specimen in original collection tube, refrigerated (2-8°C or 36-46°F) prior to transport.

Transport: 5.0 mL blood or 2.0 mL bone marrow, refrigerated (2-8°C or 36-46°F) in original collection tube. (Minimum: 1.0 mL blood or 0.5 mL bone marrow)

Storage

Specimen Stability for Testing:

Room temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 48 hours
Frozen (-20°C/-4°F or below): Unacceptable

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to the University of Michigan, Ann Arbor, MI.

Performed

Monday – Friday.
Results available in 3-8 days.

Reference Range

Negative (no mutations).

Test Methodology

Multiplex Polymerase Chain Reaction (PCR) followed by DNA Sequencing Analysis.

CPT Codes

81120, 81121.

Contacts

Last Updated

10/23/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.