Lab Test

High Molecular Weight Kininogen

HMWK, Fitzgerald Factor , LabCorp #500460, Esoterix #300123, EPIC: LAB6271, SOFT: XHMWK

Specimen Collection Criteria

Collect: Two Light Blue-top Sodium Citrate tubes.

  • Transport specimen to the Laboratory immediately after collection for processing.

Physician Office/Drawsite Specimen Preparation

For optimal results, maintain whole blood Sodium Citrate specimens at room temperature (20-26°C or 68-78.8°F) prior to transport. Transport whole blood to the Laboratory within 4 hours of collection. If transport within 4 hours is not possible, the following procedure must be followed for accurate results:

  1. Centrifuge the capped tube at 1500 x g for 15 minutes.
  2. Transfer plasma with a plastic pipette into a plastic polypropylene centrifuge tube, cap and centrifuge an additional 15 minutes at 1500 x g to obtain platelet poor plasma (PPP) which has a platelet count less than 10 bil/L. Plasma with a platelet count of less than 10 bil/L is critical for accurate results.
  3. Immediately transfer the PPP into two plastic tubes, 1.0 mL in each tube.
  4. Freeze (-20°C/-4°F or below) the PPP specimens immediately.
  5. Transport frozen on DRY ICE. Specimen must remain frozen during transport. 

Preparation for Courier Transport

Transport: Whole blood in Sodium Citrate at room temperature (20-26°C or 68-78.8°F), or plasma obtained through the process listed above, frozen (-20°C/-4°F or below).

Rejection Criteria

  • Specimens not collected or processed as indicated.


Results available in 3-9 days. 

Reference Range


Test Methodology



By report.

Clinical Utility

Measurement of high molecular weight kininogen concentration.

CPT Code


Test Codes

LabCorp #500460, Esoterix #300123, EPIC: LAB6271, SOFT: XHMWK

Last Updated


Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.


This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.