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Fungal Antibodies, CF (Southeast Michigan Only)

Fungal Antibodies by Complement Fixation

Test Codes

EPIC: LAB1231555, Beaker: XFGCF, ARUP #3000235

Department

Send Outs

Instructions

• This assay includes: Aspergillus Antibody (CF), Blastomyces Antibody, Coccidioides Antibody (CF), and Histoplasma Antibodies (CF).
• Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute samples. Please mark sample plainly as "acute" or "convalescent."

Specimen Collection Criteria

Collect: One Gold-top SST tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.4 mL)

Rejection Criteria

• Severely lipemic specimens.
• Hemolyzed Specimen.
• Contaminated Specimen.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.4 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Saturday – Sunday.
Results available in 3-7 days.

Reference Range

By report.

Test Methodology

Semi-Quantitative Complement Fixation/Semi-Quantitative Enzyme-linked Immunosorbent Assay/Qualitative Immunodiffusion.

Interpretation

Negative fungal serology does not rule out the possibility of current infection.

Clinical Utility

This assay aids in the diagnosis of an infection with Aspergillus, Blastomyces, Coccidioides, and Histoplasma.

CPT Codes

86606, 86612, 86635, 86698x2, if reflexed; 86612.

Contacts

Last Updated

10/25/2024