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Fructosamine (Southeast Michigan Only)

Glycated Albumin, Glycated proteins

Test Codes

EPIC: LAB1231320, Beaker: XFRUC, Warde: FRUC

Department

Send Outs

Instructions

High levels of ascorbic acid interfere with the fructosamine assay. Patients should abstain from ascorbic acid supplements for a minimum of 24 hours prior to specimen collection.

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube, Dark Green-top Sodium Heparin tube, or Lavendar-top EDTA tube.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within 4 hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Rejection Criteria

• Severely hemolyzed specimens.
• Icteric specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within 4 hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 2 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Warde Medical Laboratory, Ann Arbor, MI.

Performed

Monday, Wednesday, Friday
Results available in 2-5 days.

Reference Range

Age      Range

<=18   Not established

19-65  151-300 μmol/L

>=66   Not established

Test Methodology

Quantitative Spectrophotometry.

Interpretation

Ascorbic acid levels greater than 5 mg/dL may cause significant negative interference. Alpha-Methyldopa and dobesilate calcium cause artificially high values at therapeutic levels. Dysproteinemia may produce erroneous fructosamine values.

Clinical Utility

Fructosamine (glycated plasma protein) aids in monitoring long-term glycemic control in diabetics; it reflects glycemic control during the previous 2-3 weeks. Fructosamine is useful in patients in whom hemolysis is occurring or has recently occurred. In such patients the hemoglobin A1c (or glycated hemoglobin) may be lower than expected due to red cell destruction.

CPT Codes

82985
LOINC:  15069-8

Contacts

Last Updated

10/25/2024