DHEA (Dehydroepiandrosterone), Serum
DHEA , MAYO: DHEA, EPIC: LAB6000, SOFT: XDHEA
Specimen Collection Criteria
Collect (preferred specimen): One plain Red-top tube.
Send specimen for processing immediately after collection.
Physician Office/Drawsite Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and freeze (-20°C/-4°F or below).
Preparation for Courier Transport
Transport: 1.0 mL serum, frozen (-20°C/-4°F or below). (Min: 0.45 mL)
- Grossly hemolyzed specimens.
- Grossly lipemic specimens.
- Specimens not collected and processed as indicated.
Monday - Friday.
Results available 3-7 days.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Patients with Cushing's disease may have increased DHEA and increased cortisol levels, and patients with congenital adrenal hyperplasia may have increased DHEA level and decreased cortisol level. However, DHEA currently has not been established for the purpose of differential diagnosis.
Administration of ACTH increases DHEA secretion. Administration of corticosteroids decreases DHEA.
Elevated plasma DHEA concentrations are suggestive of a heterozygous form of 21-hydroxylase deficiency. Patients with hyperandrogeny of adrenal origin often have an elevated DHEA: androstenedione ratio.
MAYO: DHEA, EPIC: LAB6000, SOFT: XDHEA
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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.