Laboratory Lab results are too important to go anywhere else.

Cyclic Citrullinated Peptide AB Level

CCP, Anti-CCP, Anti-Cyclic Citrullinated Peptide Antibody, CCP 3.1 IgG/IgA, Cyclic Citrullinated Peptide Antibody (CCP 3.1 IgG, IgA)

Test Codes

EPIC: LAB3670, Beaker: CYCP, Antrim #32003

Department

Immunology

Specimen Collection Criteria

Collect: One Gold-top SST tube. (Minimum Whole Blood: 2.0 mL)

Physician Office/Draw Specimen Preparation

Preparation for Courier Transport

Transport: Centrifuged collection tube, refrigerated (2-8 °C or 36-46 °F). (Minimum Serum: 0.5 mL)

In-Lab Processing

Let specimen clot 30-60 minutes then immediately centrifuge to separate serum from cells. Room temperature is acceptable for a maximum of two hours. (Minimum Serum: 0.5 mL)

Storage

Specimen Stability for Testing:

Centrifuged SST Tubes and Microtainers^® with Separator Gels
Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Red-top Tubes and Microtainers^® without Separator Gels
Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Royal Oak Special Testing Laboratory

Performed

Seven days a week.
Results available within 2 business days.

Reference Range

Positive, Negative.

Test Methodology

Multiplex Flow Assay.

Interpretation

A positive result indicates a high likelihood of rheumatoid arthritis. Positive results may be seen in patients with other connective tissue disorders, e.g., SLE.

Clinical Utility

Anti-CCP is considered to be useful in the diagnosis and prognosis of patients with rheumatoid arthritis (RA), particularly in early cases of the disease when a patient's signs/symptoms may not fulfill the American College of Rheumatologists' classification criteria for RA. Anti-CCP has been found to have a similar sensitivity (50-75%) but a higher specificity (90-95%) when compared to rheumatoid factor (RF) in the diagnosis of RA. It has been suggested that the test may also be useful as a marker of erosive disease in RA and consequently be used to decide the type of treatment a patient should receive. However further studies are needed to support this suggestion.

CPT Codes

86200

Contacts

Last Updated

10/22/2024