Lab Test

Crystal Exam in Synovial Fluid

Synovial Fluid Analysis

Test Codes

EPIC: LAB213

Department

Hematology

Specimen Collection Criteria

Collect: 1.0 mL synovial fluid in a Green-top Sodium Heparin tube (Minimum: 0.5 mL) or sterile cup.

  • Crystal identification should not be performed on Lavender-top EDTA tubes, as powdered EDTA may produce false positive results.
  • Specimens collected in Red-top tubes are no longer acceptable.

Physician Office/Draw Specimen Preparation

Arrange for transportation to the Laboratory prior to specimen collection. Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 1.0 mL synovial fluid, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

  • Specimens received in bags, bottles, or syringes.
  • Specimens received on ice.
  • Specimens collected in Lavender-top EDTA tubes, Oxalate, Green-top Lithium Heparin tubes, or Red-top tubes.

    Inpatient Specimen Preparation

    Transport specimen to the Laboratory immediately after collection.

    Storage

    Specimen Stability for Testing:

    Room Temperature (20-26°C or 68-78.8°F): 8 hours
    Refrigerated (2-8°C or 36-46°F): 24 hours
    Frozen (-20°C/-4°F or below): Unacceptable

    Specimen Storage in Department Prior to Disposal:

    Refrigerated (2-8°C or 36-46°F): 30 days

    Laboratory

    Dearborn Hematology Laboratory
    Farmington Hills Hematology Laboratory
    Grosse Pointe Hematology Laboratory
    Royal Oak Hematology Laboratory
    Troy Hematology Laboratory

    Performed

     Site: Performed:  24-hours a day 
     Farmington Hills Hematology Laboratory   Sunday – Saturday
     Grosse Pointe Hematology Laboratory Sunday – Saturday
     Royal Oak Hematology Laboratory Sunday – Saturday
     Troy Hematology Laboratory Sunday – Saturday
      
     Site:
     Performed:  Day Shift Only
     Dearborn Hematology Laboratory Monday – Friday
      
     DOES NOT PERFORM: 
     Canton Laboratory 
     Lenox Laboratory 
     Trenton Laboratory 
     Livonia Laboratory 
     Taylor Laboratory 
     Wayne Laboratory 


    Reference Range

    Absent.

    Test Methodology

    Polarizing Microscope.

    Interpretation

    The presence of monosodium urate crystals is usually diagnostic of gout. The presence of calcium pyrophosphate dihydrate crystals is characteristic of "CPPD crystal deposition disease" or pseudogout.

    Clinical Utility

    This test can assist in the diagnosis of gout, pseudogout, and other arthritic diseases. The types of crystals found in synovial fluid include monosodium urate, calcium pyrophosphate dihydrate, cholesterol, or steroid.

    CPT Codes

    89060

    LOINC:
    38458-6

    Contacts

    Last Updated

    11/21/2024

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