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Complete Blood Count with Differential (CBCWD)

CBCWD, CBC/DIFF, CBC/D, Peripheral Smear

Test Codes

EPIC: LAB293

Department

Hematology

Specimen Collection Criteria

Collect (preferred specimen): One 4.0 mL Lavender-top K₂EDTA tube. (Minimum: 2.0 mL)
Also acceptable: One Lavender-top K₂EDTA Microtainer^®. (Minimum: 300 mcL)
See Minimum Pediatric Specimen Requirements for Microtainer^® collection.

Note: For known platelet clumper patients, see (link order). 

Physician Office/Draw Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport. Room temperature (20-26°C or 68-78.8°F) is acceptable for a maximum of 8 hours.

Preparation for Courier Transport

Transport: Whole blood or capillary blood, refrigerated (2-8°C or 36-46°F). (Minimum: 2.0 mL whole blood or 300 mcL capillary blood)

Rejection Criteria

• Specimens containing clots.
• Insufficient volume.
• Specimens received on ice.
• Frozen specimens.
• Centrifuged specimens. 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 72 hours
Frozen (-20°C/-4°F or below): Unacceptable

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 5 days

Laboratory

Canton Laboratory
Dearborn Hematology Laboratory
Farmington Hills Hematology Laboratory
Grosse Pointe Hematology Laboratory
Lenox Laboratory
Livonia Laboratory
Royal Oak Hematology Laboratory
Taylor Hematology Laboratory
Trenton Hematology Laboratory
Troy Hematology Laboratory
Wayne Hematology Laboratory

Performed

Sunday – Saturday, 24 hours a day.
Stat results available in 30 minutes; 60 minutes if further verification is necessary.
Routine results available within 90 minutes, unless further verification is necessary.

Reference Range

Parameter	Female	Male
WBC (10*9/L)	3.3-10.7	3.5-10.1
RBC (10*12/L)	3.87-5.08	4.31-5.48
Hemoglobin (g/dL)	12.1-15.0	13.5-17.0
HCT (%)	35.4-44.2	40.1-50.1
MCV (fL)	80.0-100.0	80.0-100.0
MCH (pg)	28.0-33.0	28.0-33.0
MCHC (g/dL)	32.0-35.0	32.0-35.0
RDW-CV (%)	12.0-15.0	12.0-15.0
Platelet (10*12/L)	150-400	150-400
MPV (fL)	7.4-11.0	7.4-11.0
IPF (%)	0.9-8.5	0.9-8.5
Differential
Neutrophils (10*9/L)	1.60-7.20	1.60-7.20
Lymphocytes (10*9/L)	1.10-4.00	1.10-4.00
Monocytes (10*9/L)	0.00-0.80	0.00-0.90
Eosinophils (10*9/L)	0.00-0.50	0.00-0.40
Basophils (10*9/L)	0.00-0.10	0.00-0.10
IG (10*9/L)	0.0-0.03	0.0-0.04

Please see Hematology Pediatric Reference Range.

NOTE: All orders with a WBC < 0.4 10*9/L will not have a differential resulted. The order will be changed to a CBC w/o differential. 

Test Methodology

SYSMEX XN Series.

Clinical Utility

This assay measures the hematologic parameters of the blood. It aids in the evaluation of anemia, leukemia, reaction to inflammation and infections, peripheral blood cell characteristics, state of hydration and dehydration, polycythemia, hemolytic disease of the newborn, and ABO incompatibilities.

NOTE: For inpatients receiving chemotherapy, the order does not flag for critical WBC or platelet. For outpatients receiving chemotherapy, the order does not flag for critical WBC. 

CPT Codes

CBC with automated diff: 85025
CBC with manual diff: 85027, 85007

LOINC:
WBC: 6690-2
RBC: 789-8
HGB: 718-7
HCT: 4544-3
MCV: 787-2
MCH: 785-6
MCHC: 786-4
RDW-CV: 788-0
Platelet: 777-3
MPV: 32623-1
NRBC: 58413-6
Neutrophil Absolute: 751-8
Lymphocyte Absolute: 731-0
Monocyte Absolute: 742-7
Eosinophil Absolute: 711-2
Basophil Absolute: 704-7
Immature Gran Absolute: 53115-2

Contacts

Last Updated

8/15/2024