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Chlorpromazine Level

Thorazine, Ormazine, Largactil

Test Codes

EPIC: LAB5974, Beaker: XCPL, ARUP #3003036

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below).

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Rejection Criteria

• Serum Separator (SST) Tube.
• Whole blood
• Hemolyzed specimens
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below).

Transport: 2.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 14 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday.
Results available within 8 days.

Reference Range

See report.

Test Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Chlorpromazine is used to treat psychotic disorders (e.g., schizophrenia), control nausea and vomiting, relieve restlessness prior to surgery, treat acute intermittent porphyria, control the manic phase in bipolar disorders, to treat intractable hiccups, and treat problems in children characterized by hyper-excitable, aggressive stages. This assay is used for the therapeutic monitoring and toxicity assessment of Chlorpromazine.

CPT Codes

80342 (alternate code: G0480).
LOINC:  3471-0

Contacts

Last Updated

2/10/2024