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Cadmium, Blood

Test Codes

EPIC: LAB736, Beaker: XCD, Mayo: CDB

Department

Send Outs

Instructions

High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Specimen Collection Criteria

Collect: One Royal Blue-top EDTA tube.

Physician Office/Draw Specimen Preparation

Do not centrifuge. Maintain at room temperature (20-26°C or 68-78.8°F) in original collection tube prior to transport.

Preparation for Courier Transport

Transport: 6.0 mL whole blood, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Do not centrifuge. Maintain at room temperature (20-26°C or 68-78.8°F) in original collection tube prior to transport.

Transport: 6.0 mL whole blood, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 28 days
Refrigerated (2-8°C or 36-46°F): 28 days
Frozen (-20°C/-4°F or below): 28 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN.

Performed

Monday – Saturday.
Results available within 2-4 days.

Reference Range

By report.

Test Methodology

Quantitative Inductively Coupled Plasma/Mass Spectrometry.

Interpretation

Elevated results from non-certified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designated for trace element determinations, such as royal blue (K₂EDTA) tube.

Clinical Utility

This assay is used to evaluate cadmium toxicity in industrial exposure to cadmium fumes or cadmium ingestion. Chronic exposure to cadmium causes cumulative renal damage. It has also been implicated in pulmonary disease, cancer, hypertension, and myocardial abnormalities. OSHA mandates that all workers at risk be monitored by measuring blood and urine cadmium and urine beta-2 microglobulin as a marker for kidney damage. Blood cadmium estimates current cadmium exposure. Urine cadmium estimates cadmium body burden.

CPT Codes

82300
LOINC:  77307-7

Contacts

Last Updated

7/21/2024