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Aspergillus Antigen

Aspergillosis Galactomannan Antigen

Test Codes

BAL: EPIC: LAB1230142, Viracor: 1609, CSF: EPIC: LAB1230141, Viracor: 1603, Serum: EPIC: LAB1230143, Viracor: 1610, Bronch Wash: EPIC: LAB1230144, Viracor: 1626

Department

Send Outs

Specimen Collection Criteria

Collect: One Gold-top SST tube or plain Red-top tube.
Also acceptable: Bronchoalveolar Lavage (BAL), Cerebrospinal Fluid (CSF) or Bronchial Wash in a sterile container.

Send specimen for processing immediately after collection.

Physician Office/Draw Specimen Preparation

Let blood specimens clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube at room temperature (20-26°C or 68-78.8°F): Maintain BAL, CSF, or Bronchial Wash specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL serum at room temperature (20-26°C or 68-78.8°F), BAL, CSF or Bronchial Wash frozen (-20°C/-4°F or below. (Minimum: 0.5 mL)

Rejection Criteria

• Urine specimens.
• Specimens not collected and processed as indicated.
• Hemolyzed specimens.
• Icteric specimens.
• Lipemic specimens.

In-Lab Processing

Let blood specimens clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and keep at room temperature (20-26°C or 68-78.8°F). Maintain BAL, CSF and Bronchial Wash specimens frozen (-20°C/-4°F or below) prior to transport.

Transport: 2.0 mL serum at room temperature (20-26°C or 68-78.8°F), BAL, CSF or Bronchial Wash frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Serum
Room Temperature (20-26°C or 68-78.8°F): 30 days
Refrigerated (2-8°C or 36-46°F): 30 days
Frozen (-20°C/-4°F or below): Unknown

CSF
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 7 days

BAL and Bronchial Wash
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 5 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Viracor/Eurofin Lab Lenexa, KS.

Performed

Monday – Saturday.
Results available in 1-2 days.

Reference Range

By report.

Test Methodology

One Stage Immunoenzymatic Sandwich Microplate Assay.

Interpretation

False positive results can be caused by infection with Penicilium, Alternaria and Paecilomyces. Patients with Histoplasmosis and other endemic myscoes may also cause false positives. Antifungal therapy may reduce the assays sensitivity.

Clinical Utility

This test is an aid in the early diagnosis of invasive aspergillosis and, along with other diagnostic tests and clinical signs of disease, allows for the effective early treatment of the disease.

CPT Codes

87305

Contacts

Last Updated

10/16/2024