Lab Test

Alpha 1 Antitrypsin, Fecal

Alpha-1-Antitrypsin , MAYO: A1AF, EPIC: LAB5930, SOFT: XA1AF

Specimen Collection Criteria

Collect: 5.0 gram random stool specimen in a sterile collection container. (Min: 1.0 mL homogenized stool)

Physician Office/Drawsite Specimen Preparation

Maintain specimen frozen (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: 5.0 gram random stool, frozen (-20°C/-4°F or below). (Min: 1.0 mL homogenized)

Rejection Criteria

  • Specimens not collected and processed as indicated.

Performed

Monday - Saturday.
Results available in 2-4 days.

Reference Range

Less than or equal to 54 mg/dL.

Test Methodology

Nephelometry.

Interpretation

By report.

Clinical Utility

This assay aids in the diagnosis of protein-losing enteropathy. The recommended assay for this diagnosis is the alpha-1-antitrypsin clearance (feces and serum). In the absence of a 24-hour stool collection and/or a contemporary serum specimen, the fecal concentration of alpha-1-antitrypsin can be used as a plasma marker. The clearance is preferred in order to normalize the large range of serum alpha-1-antitrypsin concentrations.

CPT Code

82103.

Test Codes

MAYO: A1AF, EPIC: LAB5930, SOFT: XA1AF

Last Updated

7/11/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.