Lab Test

Alpha 1 Acid Glycoprotein

Alpha-1-Acid Glycoprotein, Alpha-1 Acid Glycoprotein, NEPH , QUEST #551642, EPIC: LAB6512, SOFT: XAAG

Specimen Collection Criteria

Collect: One plain Red-top tube.
Also acceptable: One Gold-top SST tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.


Ambient: 72 hours
Refrigerated: 14 days
Frozen:  2 months


Tuesday - Saturday.
Results available in 3-5 days.

Reference Range

By report.

Test Methodology

Fixed Rate Time Nephelometry.


Levels are increased in acute inflammation.

Clinical Utility

Alpha-1-acid glycoprotein is an acute phase reactant whose role is unknown. Early work indicated that the liver is the only site of synthesis, but more recent studies have shown that some tumors are also able to synthesize it. Clinically, alpha-1-acid glycoprotein is used for monitoring acute phase reactions such as inflammatory conditions, rheumatoid arthritis, and malignant neoplasms.

CPT Code


Test Codes

QUEST #551642, EPIC: LAB6512, SOFT: XAAG

Last Updated


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This directory currently reflects information only for specimens collected and/or processed at the
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