Lab Test

Porphyrins and Porphobilinogen (PBG), Urine, Quantitative (Southeast Michigan Only)

Test Codes

EPIC: LAB1231258, Beaker: XPORPBGU, ARUP: 2002181

Department

Send Outs

Instructions

Specimen Collection Criteria

Collect (preferred specimen): 24-hour urine sample with no preservative.

  • Keep 24-hour urine specimen iced or refrigerated during collection.
  • Include start and end dates and times for the collection period on the specimen container.
  • All specimens must be protected from light.

Urine Preservative Options

No Preservative

6N Hydrochloric Acid

Boric Acid (10g)

Sodium Carbonate

50% Acetic Acid

REQUIRED

Unacceptable

Unacceptable

Unacceptable

Unacceptable


Physician Office/Draw Specimen Preparation

Protect specimen from light. Maintain specimens frozen (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: Entire 24-hour urine collection.

Rejection Criteria

Specimens not collected and processed as indicated. 

In-Lab Processing

Protect specimen from light. Measure total volume of 24-hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot 8.0 mL from the well-mixed 24-hour urine collection and freeze (-20°C/-4°F or below). (Minimum: 4.0 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 4 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Sunday – Saturday.
Results available in 2-5 days.

Reference Range

By report.

Test Methodology

Quantitative High Performance Liquid Chromatography/Quantitative Spectrophotometry/Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Urine porphyrins are useful for the evaluation of cutaneous photosensitivity to exclude porphyria cutanea tarda (PCT). Urine porphobilinogen (PBG) is useful for the evaluation of neurologic and/or psychiatric symptoms to exclude acute porphyrias such as acute intermittent porphyria (AIP).

CPT Codes

84120, 84110.

Contacts

Last Updated

11/12/2024

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.