Lab Test

Olanzapine

Zyprexa®, ARUP #98833, EPIC: LAB6117, SOFT: XOLAN

Test Codes

ARUP #98833, EPIC: LAB6117, SOFT: XOLAN

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tubes.
Also acceptable: One Lavender-top EDTA tubes.

Do not use Serum Separator Tubes.

Time of Collection: Trough, just prior to the next dose.
Critical frozen. Send specimen for processing immediately after collection.

Physician Office/Draw Specimen Preparation

Critical frozen. Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 1.0 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated. 

In-Lab Processing

Critical frozen. Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Transport: 2.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 1.0 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): 14 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday, Wednesday, Saturday.
Results available in 2-6 days.

Reference Range

Therapeutic Range: 20-80 ng/mL.
Toxic Range: Not well established.

Test Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Interpretation

By report.

Clinical Utility

This assay aids in the therapuetic drug monitoring of Olanzapine (Zyprexa®) an antipsychotic agent. Zyprexa® is indicated for the management of the manifestations of psychotic disorders.

CPT Codes

80342 (alternate code: G0480).

Contacts

Last Updated

10/23/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.