Lab Test

Olanzapine

Zyprexa® , ARUP #98833, EPIC: LAB6117, SOFT: XOLAN

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tubes.
Also acceptable: One Lavender-top EDTA tubes.

Do not use Serum Separator Tubes.

Time of Collection: Trough, just prior to the next dose.
Critical frozen. Send specimen for processing immediately after collection.

Physician Office/Drawsite Specimen Preparation

Critical frozen. Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Min: 1.0 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated. 

Storage

Ambient: Unacceptable
Refrigerated: Unacceptable
Frozen: 6 months

Performed

Wednesday, Saturday.
Results available in 2-6 days.

Reference Range

Therapeutic Range: 20-80 ng/mL.
Toxic Range: Not well established.

Test Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Interpretation

By report.

Clinical Utility

This assay aids in the therapuetic drug monitoring of Olanzapine (Zyprexa®) an antipsychotic agent. Zyprexa® is indicated for the management of the manifestations of psychotic disorders.

CPT Code

80342 (alternate code: G0480).

Test Codes

ARUP #98833, EPIC: LAB6117, SOFT: XOLAN

Last Updated

7/11/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.