Lab Test

Endomysial Antibody, IgG

IgG EmA , QUEST #91985, WARDE: ENDG, EPIC: LAB7079, SOFT: XENDG

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within one hour of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.2 mL)

Rejection Criteria

  • Grossly hemolyzed specimens.
  • Lipemic specimens.
  • Specimens not collected and processed as indicated.

Performed

Monday - Friday.
Results available in 4-10 days.

Reference Range

By report.

Test Methodology

Indirect Fluorescent Antibody.

Clinical Utility

Gluten-sensitive enteropathy is characterized as a non-allergic hypersensitivity to gluten or storage proteins found in wheat and other cereals. This hypersensitivity causes intestinal villous atrophy resulting in malabsorption. The Endomysial IgG Antibody assay may aid in the diagnosis of gluten-sensitivity enteropathy (i.e., celiac disease, dermatitis herpetiformis) in Endomysial IgA negative patients with confirmed IgA deficiency. A negative Endomysial IgG test alone does not rule out gluten-sensitive enteropathy. These antibodies generally decrease or become negative in patients on gluten-free diets and will usually reappear upon gluten challenge.

CPT Code

86255, 86256 (if indicated).

Test Codes

QUEST #91985, WARDE: ENDG, EPIC: LAB7079, SOFT: XENDG

Last Updated

7/11/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.