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Coxsackie B Antibody Types 1-6

Coxsackie B Virus Antibodies

Test Codes

EPIC: LAB5995, Beaker: XCOXB, ARUP: 60055

Department

Send Outs

Instructions

Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute samples. Please mark sample plainly as "acute" or "convalescent".

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube, or 1.0 mL cerebrospinal fluid (CSF) in a sterile collection container. (Minimum: 0.3 mL)

Physician Office/Draw Specimen Preparation

• Let serum specimens clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).
• Maintain CSF specimens refrigerated prior to transport.

Preparation for Courier Transport

Transport: 1.0 mL serum or CSF, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Rejection Criteria

• Hemolyzed specimens.
• Severely lipemic specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

• Let serum specimens clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).
• Maintain CSF specimens refrigerated prior to transport.

Transport: 1.0 mL serum or CSF, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday – Friday.
Results available in 7-10 days.

Reference Range

Coxsackie B1: Less than 1:10.
Coxsackie B2: Less than 1:10.
Coxsackie B3: Less than 1:10.
Coxsackie B4: Less than 1:10.
Coxsackie B5: Less than 1:10.
Coxsackie B6: Less than 1:10.

Test Methodology

Semi-Quantitative Serum Neutralization.

Interpretation

Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection. 

CPT Codes

86658 x 6.
LOINC:  Type 1  5103-7, Type 2  5105-2, Type 3  5107-8, Type 4  5109-4, Type 5  5111-0, Type 6  5113-6

Contacts

Last Updated

10/3/2023