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Chemo Complete Blood Count with Differential

Chemo CBC with Differential, Chemo CBC/DIFF, Chemo CBC/D

Test Codes

EPIC: LAB6877, Antrim: 27090

Department

Hematology

Instructions

This test should only be ordered on Hem/Onc patients receiving chemotherapy. Inpatient order does not flag for critical WBC or platelet. Outpatient order does not flag for critical WBC.

Specimen Collection Criteria

Collect (preferred specimen): One 4.0 mL Lavender-top K₂EDTA tube. (Minimum: 2.0 mL)
Also acceptable: One Lavender-top K₂EDTA Microtainer^®. (Minimum: 300 mcL)
See Minimum Pediatric Specimen Requirements for Microtainer^® collection.

NOTE: For known platelet clumper patients, collect one light blue top 3.2% sodium citrate tube (ensure tube is full) and one 4.0 mL lavender-top K2EDTA tube (minimum: 2.0 mL). Label both tubes with the order requested and rubber band the two tubes together. Place a handwritten note with the samples stating “Previous platelet clumper. Deliver both tubes to the hematology lab.”

Physician Office/Draw Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport. Room temperature (20-26°C or 68-78.8°F) is acceptable for a maximum of 8 hours.

Preparation for Courier Transport

Transport: Whole blood or capillary blood, refrigerated (2-8°C or 36-46°F). (Minimum: 2.0 mL whole blood or 300 mcL capillary blood)

Rejection Criteria

• Specimens containing clots.
• Insufficient volume.
• Frozen specimens.
• Centrifuged specimens. 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 72 hours
Frozen (-20°C/-4°F or below): Unacceptable

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Canton Laboratory
Dearborn Hematology Laboratory
Farmington Hills Hematology Laboratory
Grosse Pointe Hematology Laboratory
Lenox Laboratory
Livonia Laboratory
Royal Oak Hematology Laboratory
Taylor Hematology Laboratory
Trenton Hematology Laboratory
Troy Hematology Laboratory
Wayne Hematology Laboratory

Performed

Sunday – Saturday, 24 hours a day.
STAT results available in 30 minutes; 60 minutes if further verification is necessary.
Routine results available within 90 minutes, unless further verification is necessary.

Reference Range

Parameter	Female	Male
WBC (bill/L)	3.3-10.7	3.5-10.1
RBC (tril/L)	3.87-5.08	4.31-5.48
Hemoglobin (g/dL)	12.1-15.0	13.5-17.0
HCT (%)	35.4-44.2	40.1-50.1
MCV (fL)	80-100	80-100
MCH (pg)	28-33	28-33
MCHC (g/dL)	32-35	32-36
RDW-SD (fL)	40-50	37-47
RDW-CV (%)	12-15	12-15
Platelet (bill/L)	150-400	150-400
Differential
Neutrophils (bill/L)	1.6-7.2	1.6-7.2
Lymphocytes (bill/L)	1.1-4.0	1.1-4.0
Monocytes (bill/L)	0.0-0.8	0.0-0.9
Eosinophils (bill/L)	0.0-0.5	0.0-0.4
Basophils (bill/L)	0.0-0.1	0.0-0.1
IG (bill/L)	0.0-0.03	0.0-0.04

Please see Hematology Pediatric Ranges.

NOTE: All orders with a WBC < 0.4 bill/L will not have a differential resulted. The order will be changed to a CBCND.

Test Methodology

SYSMEX XN Series or XE Series.

Clinical Utility

This assay measures the hematologic parameters of the blood. It aids in the evaluation of anemia, leukemia, reaction to inflammation and infections, peripheral blood cell characteristics, state of hydration and dehydration, polycythemia, hemolytic disease of the newborn, and ABO incompatibilities.

NOTE: This test should only be ordered on Hem/Onc patients receiving chemotherapy. Inpatient order does not flag for critical WBC or platelet. Outpatient order does not flag for critical WBC.

CPT Codes

85025

Contacts

Last Updated

7/21/2024