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Beaumont Laboratory

Mephenytoin and Metabolite

Mesantoin, Nivarnol, ARUP #91110, EPIC: LAB6095, SOFT: XMEPH

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube or Dark Green-top Sodium Heparin tube.

Do not use Serum Separator Tubes.

Time of Collection: Trough, just prior to the next dose.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Min: 0.7 mL)

Rejection Criteria

  • Serum Separator (SST) tubes.
  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 14 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 13 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Varies.
Results available in 4-11 days.

Reference Range

By report.

Test Methodology

Quantitative High Performance Liquid Chromatography.

Interpretation

By report.

Clinical Utility

Mephenytoin is used for the control of grand mal, focal, Jacksonian, and psycho-motor seizures in those patients who have been refractory to less toxic anticonvulsants. This assay is used to monitor the therapeutic drug level and to evaluate the toxicity of mephenytoin.

CPT Code

80339 (alternate code: G0480).

Test Codes

ARUP #91110, EPIC: LAB6095, SOFT: XMEPH

Last Updated

08/30/2017

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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.