Hypoglycemic Agent Screen
Sulfonylureas (chlorpropamide, tolazamide, tolbutamide, acetohexamide, glipizide, glyburide, glimepiride), Meglitinides (repaglinide), MAYO: HYPOG, EPIC: LAB6279, SOFT: XHYPG
Specimen Collection Criteria
Collect: One plain Red-top tube.
Do not use Serum Separator Tubes.
Physician Office/Drawsite Specimen Preparation
Let specimen clot 30-60 minutes and centrifuge to separate serum from cells. Transport serum to a plastic transport tube and freeze (-20°C/-4°F or below).
Preparation for Courier Transport
Transport: 3.0 mL serum, frozen (-20°C/-4°F or below). (Min: 1.1 mL)
- Serum Separator (SST) tubes.
- Grossly icteric specimens.
- Grossly lipemic specimens.
- Specimens not collected and processed as indicated.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 14 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 14 days
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.
Sent to Mayo Medical Laboratories, Rochester, MN.
Monday, Wednesday, Friday.
Results available in 3-9 days.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
The metabolic and hormonal profiles of insulinoma and sulfonylurea-induced hypoglycemia are identical. Therefore, in the evaluation of the hypoglycemic patient, the possible use of oral hypoglycemic agents as the cause for low blood glucose and elevated plasma insulin must be considered. Absence of hypoglycemic drugs in blood serum during an episode of low blood glucose should be demonstrated before considering pancreatic exploration for suspected insulinoma.
MAYO: HYPOG, EPIC: LAB6279, SOFT: XHYPG
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UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.
This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills,
Grosse Pointe, Royal Oak, and Troy campuses.