IL2, IL-2, T-Cell Growth Factor, (TCGF), Thymocyte Stimulation Factor, (TSF), Thymocyte Mitogenesis Factor, (TMF), T-Cell Replacing Factor, (TRF), Killer Helper Factor, (KHF), Interleukin 2 by MAFD, Interleukin-2, ARUP #51588, Antrim #81210, EPIC: LAB7072, SOFT: XINT2
Specimen Collection Criteria
Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube or Dark Green-top Lithium Heparin tube.
Critical frozen. Send specimens for processing immediately after collection.Separate samples must be submitted when multiple tests are ordered.
Physician Office/Drawsite Specimen Preparation
Critical frozen. Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma into a plastic transport tube and freeze (-20°C/-4°F or below) immediately.
Preparation for Courier Transport
Transport: 1.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Min: 0.3 mL)
- Specimens not collected and processed as indicated.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 30 minutes
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): 1 year
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.
Sent to ARUP Laboratories, Salt Lake City, UT.
Monday, Wednesday, Friday.
Results available in 2-5 days.
Less than 12 pg/mL.
Quantitative Multiplex Bead Assay.
Interleukin 2 (IL-2) is a glycoprotein produced by activated T-cells that has a variety of immunologic functions, the most notable being the ability to promote the proliferation and maturation of activated T-cells. IL-2 has been known by various names, including T-Cell Growth Factor (TCGF), Thymocyte Stimulation Factor (TSF), Thymocyte Mitogenesis Factor (TMF), T-Cell Replacing Factor (TRF), and Killer Helper Factor (KHF).
This test uses a kit designated by the manufacturer as "for research use, not for clinical use." The performance characteristics of this test were validated by ARUP Laboratories, Inc. The U.S. Food and Drug Administration (FDA) has not approved this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. ARUP is authorized under Clinical Laboratory Improvement Amendments (CLIA) and by all states to perform high-complexity testing.
Decreased production of this cytokine has been associated with the following disease states: systemic lupus erythematosus (SLE), Hodgkin's disease, lepromatous leprosy and AIDS. The ability of IL-2 to stimulate killer cells and enhance their cytotoxicity has led to the combined usage of IL-2 and lymphocyte activated killer cells (LAK) for the treatment of certain cancers.
ARUP #51588, Antrim #81210, EPIC: LAB7072, SOFT: XINT2