Beaumont Laboratory - Lab Test Details
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Beaumont Laboratory

Lactic Acid, Plasma

Lactate, EPIC: LAB5133, SOFT: LA

Specimen Collection Criteria

Collect: One Gray-top Fluoride Oxalate tube.
(Farmington Hills Only) One Gray-top Fluoride Oxalate tube. Collect specimen on ice. Send immediately on ice to the Laboratory for processing. Uncentrifuged specimens must be received on ice within 15 minutes of collection.
See Minimum Pediatric Specimen Requirements.

Physician Office/Drawsite Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport. Room temperature (20-26°C or 68-78.8°F) is acceptable for a maximum of 8 hours.

Preparation for Courier Transport

Transport: Whole blood, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)
(Farmington Hills Only) Blood samples should be placed on ice and plasma separated from the cells within 15 minutes of collection.

Rejection Criteria

  • Moderate to grossly hemolyzed specimens.
  • Specimens not collected in fluoride oxalate tubes.
  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Plasma After Centrifugation in Fluoride Oxalate (Gray-top tubes)
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Uncentrifuged Whole Blood in Fluoride Oxalate (Gray-top tubes)
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days (aliquot separated from cells)

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days (Whole Blood)

(Farmington Hills Only):
Plasma After Centrifugation in Fluoride Oxalate (Gray-top tubes)
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days (aliquot separated from cells)

Uncentrifuged Whole Blood in Fluoride Oxalate (Gray-top tubes)
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Laboratory

Farmington Hills Chemistry Laboratory.
Grosse Pointe Chemistry Laboratory.
Royal Oak STAT Laboratory.
Troy Chemistry Laboratory.

Performed

Sunday - Saturday, 24 hours a day.
STAT results available within 1 hour of receipt in the Laboratory.
Routine results available within 4 hours.

Reference Range

0.5-2.2 mmol/L.

Test Methodology

Enzymatic.

Interpretation

Lactate is an end-product of glycolysis arising mainly in muscle, brain and RBC's. Increased levels may reflect increased rates of production and /or decreased clearance rates (by liver and kidney). Increased lactate production occurs during episodes of tissue hypoxia and anaerobic metabolism. Blood cells rapidly metabolize glucose to lactic acid- it is therefore essential to minimize glycolysis of the blood sample (see Specimen Collection Criteria).

Clinical Utility

This assay aids in the evaluation of metabolic acidosis, regional or diffuse tissue hypoperfusion, hypoxia, shock, congestive heart failure, dehydration, complicated postoperative state, ketoacidosis or nonketotic acidosis in diabetes mellitus, patients with infections, inflammatory states, certain myopathies, acute leukemia and other neoplasia, enzyme defects, glycogen storage disease (type1), thiamine deficiency and hepatic failure.

CPT Code

83605.

Test Codes

EPIC: LAB5133, SOFT: LA

Last Updated

06/28/2018

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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.