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Beaumont Laboratory

Interleukin 2 Receptor

Interleukin-2 Receptor, Interleukin 2 Receptor by MAFD, CD25, IL2, ARUP #51529, Antrim #81211, EPIC: LAB6073, SOFT: XIN2R

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube or Dark Green-top Lithium Heparin tube.

Critical frozen.  Send specimens for processing immediately after collection. Separate samples must be submitted when multiple tests are ordered.

Physician Office/Drawsite Specimen Preparation

Critical frozen. Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma into a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Min: 0.3 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated. 


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 30 minutes
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.


Sent to ARUP Laboratories, Salt Lake City, UT.


Monday, Wednesday, Friday.
Results available in 2-5 days.

Reference Range

Less than 1033 pg/mL.

Test Methodology

Quantitative Multiplex Bead Assay.


The performance characteristics of this test were validated by ARUP. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test "for Research use only, not for clinical use."

Clinical Utility

The receptor of the cytokine interleukin 2 (IL-2) plays a crucial role in the regulation of the immune response. Binding of IL-2 to the receptor (IL2R) on the surface of T-lymphocytes triggers a series of intracellular signals that result in activation and proliferation of resting T cells. Research has found sIL2R is present in elevated levels with neoplastic diseases, autoimmune diseases, organ allograft rejection and different infections. It appears the sIL2R is an indicator of a wide spectrum of disorders involving immune activation.

CPT Code


Test Codes

ARUP #51529, Antrim #81211, EPIC: LAB6073, SOFT: XIN2R

Last Updated


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UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.