Details

Hypersensitivity Pneumonitis I

ARUP #55076, EPIC: LAB6066, SOFT: XHYP1

Instructions

This panel includes:

  • Aspergillus fumigatus #1 Antibodies
  • Aspergillus fumigatus #6 Antibodies
  • Aureobasidium pullulans Antibodies
  • Pigeon serum Antibodies
  • Micropolyspora faeni Antibodies
  • Thermoactinomyces vulgaris #1 Antibodies

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.15 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.

Storage

After separation from clot:
Ambient: 2 days
Refrigerated: 14 days
Frozen: 1 year (avoid repeated freeze/thaw cycles)

Performed

Sunday - Saturday.
Results available in 4-6 days.

Reference Range

Aspergillus fumigatus #1 Antibodies: None detected.
Aspergillus fumigatus #6 Antibodies: None detected.
Aureobasidium pullulans Antibodies: None detected.
Pigeon serum Antibodies: None detected.
Micropolyspora faeni Antibodies: None detected.
Thermoactinomyces vulgaris #1 Antibodies: None detected.

Test Methodology

Qualitative Immunodiffusion.

Interpretation

Precipitating antibodies against the offending antigen can be demonstrated in most active cases of hypersensitivity pneumonitis, however, a positive test does not always indicate active disease since asymptomatic individuals may develop precipitins without any features of hypersensitivity. A positive test is a helpful diagnostic tool when supported by historical and clinical evidence. The absence of a positive test does not rule out hypersensitivity pneumonitis.

Clinical Utility

This assay aids in the diagnosis of hypersensitivity pneumonitis.

CPT Code

86331x4, 86606x2.

Test Codes

ARUP #55076, EPIC: LAB6066, SOFT: XHYP1

Last Updated

7/11/2019