Hepatitis E Ab, IgM
Hepatitis E IgM, Hepatitis E Antibody, IgM , ARUP #2010156, EPIC: LAB6622, SOFT: XHPEM
Specimen Collection Criteria
Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube or one Lavender-top EDTA tube.
Send specimen for processing immediately after collection.
Physician Office/Drawsite Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).
Preparation for Courier Transport
Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.3 mL)
- Specimens not collected and processed as indicated.
Results available in 2-9 days.
Qualitative Enzyme-Linked Immunosorbent Assay (ELISA).
Both IgM and IgG antibody to HEV (anti-HEV) are elicited following HEV infection. The titer of IgM anti-HEV declines rapidly during early convalescence. IgG anti-HEV persists and appears to provide at least short-term protection against disease.
This test is used for the in vitro detection of IgG and IgM antibodies to hepatitis E virus in human serum.
The epidemiology and clinical course of viral hepatitis E are similar to that of hepatitis A. There is no evidence of a chronic form. The case fatality rate is similar to that of hepatitis A, except in pregnant women where the rate may reach 20% during the third trimester of pregnancy.
- Benenson, Abram. Control of Communicable Diseases in Man, 15th edition, American Public Health Association, Washington, DC. 1990.
ARUP #2010156, EPIC: LAB6622, SOFT: XHPEM