Details

Horse Dander (Allergen Specific IgE)

Horse Dander (e3) , Antrim #31630, EPIC: LAB5651, SOFT: EHOR

Specimen Collection Criteria

Collect: One Gold-top SST tube.

Twenty individual allergen assays or allergen screens can be performed on one 5 mL Gold-top SST tube. Each allergen assay requires 100 mcL of serum.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged collection tube within two hours of collection.

Preparation for Courier Transport

Transport: Centrifuged collection tube, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

  • Plasma specimens.
  • Severely lipemic or hemolyzed specimens.

Storage

0,Centrifuged SST tubes may be transported and stored at ambient temperatures (2o to 30o C; 36o to 86o F) for up to 48 hours. DO NOT FREEZE TUBES CONTAINING BLOOD. For longer storage, the serum should be removed from the gel and refrigerated (2o - 8o C) or frozen at -20o C or below.

Red-top tubes and Microtainers® may be stored at ambient temperatures for up to 16 hours and for up to 3 days at refrigerator temperatures (2o - 8o C). DO NOT FREEZE TUBES CONTAINING BLOOD. For longer storage, the serum should be removed from the clot and refrigerated (2o - 8o C) or frozen at - 20o C or below.

0,Serum specimens (pour-overs) may be stored at room temperature (20o to 26o C; 68o to 79o F) for up to 1 week, refrigerator temperature (2o to 8o C; 36o to 47o F) for two weeks, and at -20o C (-4o F) for up to 3 months. Specimens stored at - 70o C (-94o F) can be stored indefinitely.

Performed

Monday - Friday.
Results available the next business day.

Reference Range

Allergy Reference Range: Less than 0.35 kU/L. 

Range (kU/L) Class Interpretation
Less than or equal to 0.34 0 Negative
0.35-0.69 1 Low
0.70-3.49 2 Medium
3.50-17.49 3 High
17.50-49.99 4 Very High
50.0-100.0 5 Very High
Greater than 100 6 Very High

Test Methodology

Fluorescence Enzyme Immunoassay (FEIA).

Interpretation

The allergen class may not be predictive of clinical disease in some patients. The diagnosis of allergy should be based upon patient history and clinical findings. The diagnosis of allergy should not be based upon laboratory findings alone.

Clinical Utility

A positive test result (class 1 or greater) is indicative of the presence of allergen-specific IgE and suggests an increased likelihood of allergic disease.

Clinical Disease

Horse dander allergies can occur throughout the year in sensitized individuals. The three major allergens that have been identified in horse dander (nonviable horse skin cells) are Equ c I, II, and III (1).

Horse dander exposure usually occurs through inhalation of aerosolized dander. Airborne transmission usually produces itchy, watery eyes, coughing, and sneezing in sensitized individuals. Skin contact with these allergens can cause dermatologic discomfort, including itching and hives. Although horse dander allergy produces the same clinical picture as cat dander allergy, the occurrence is much less common because horse dander is not typically found in the home (2).

Reference

  1. Middleton, E., Charles Reed, Elliot Ellis, N. Franklin Adkinson, John Yunginger, and William Busse. Allergy Principles and Practice. Volume I. 4th ed. Mosby: St. Louis. 1993. Pp. 536.
  2. Patterson, R. Leslie Grammar, Paul Greenberger and C. Zeiss. Allergic Diseases Diagnosis and Management. 4th ed. J.B. Lippincott Co.: Philadelphia. 1993. Pp. 139.

CPT Code

86003.

Test Codes

Antrim #31630, EPIC: LAB5651, SOFT: EHOR

Last Updated

7/11/2019