Details

Hereditary Spherocytosis Evaluation

Osmotic Fragility, Routine Osmotic Fragility, Erythrocyte Osmotic Fragility (Routine) , MAYO: RBCME, EPIC: LAB6270, SOFT: XHSPE

Instructions

  • Due to specimen stability, patients should be drawn Monday-Thursday only. For questions, call the Laboratory at (800) 551-0488.
  • A control specimen from an unrelated, non-smoking individual must be collected and sent with the patient specimen.

Specimen Collection Criteria

Collect: One Lavender-top EDTA tube from the patient AND one Lavender-top EDTA tube from an unrelated individual as a control specimen. Indicate the control's sex on the control collection tube.

Send specimens for processing immediately after collection.

Physician Office/Drawsite Specimen Preparation

Do not centrifuge. Maintain whole blood specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 4.0 mL whole blood for both patient and control specimens, refrigerated (2-8°C or 36-46°F). (Min: 2.0 mL each tube)

Rejection Criteria

  • Centrifuged specimens.
  • Hemolyzed specimens.
  • Specimens not collected and processed as indicated.

Storage

0,Specimens are stable for 2 hours at room temperature (20o to 26o C; 68o to 79o F) and for 6 hours at 2-8oC.

Performed

Monday - Saturday.
Results available in 5-8 days.

Reference Range

By report.

Test Methodology

Osmotic Lysis/Flow Cytometry.

CPT Code

85557. Add 88184, if appropriate.

Test Codes

MAYO: RBCME, EPIC: LAB6270, SOFT: XHSPE

Last Updated

7/11/2019