Inflammatory Bowel Disease Serology
IBD Panel , MAYO: IBDP, EPIC: LAB6280, SOFT: XIBDS
Specimen Collection Criteria
Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Gold-top SST tube.
Physician Office/Drawsite Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and refrigerate (2-8°C or 36-46°F).
Preparation for Courier Transport
Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)
- Grossly hemolyzed specimens.
- Grossly lipemic specimens.
- Specimens not collected and processed as indicated.
Results available in 2-3 days.
Enzyme-Linked Immunosorbent Assay (ELISA)/Indirect Fluorescent Assay (IFA).
The term "inflammatory bowel disease" (IBD) is often used to refer to 2 diseases, ulcerative colitis (UC), and Crohn's disease (CD), that produce inflammation of the large or small intestines.
Patients with IBD have been shown to have antibodies in serum that help to distinguish between UC and CD. Patients with UC often have measurable neutrophil atypical perinuclear anti cystoplasmic antibodies (Atypical P-ANCA), which react with as yet uncharacterized target antigens in human neutrophils; whereas patients with CD often have measurable antibodies, which react with the Saccharomyces cerevisia strain Su 1.
As an adjunct in the diagnosis of UC and CD in patients suspected of having IBD.
MAYO: IBDP, EPIC: LAB6280, SOFT: XIBDS
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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.