Lab Test

HTLV I/II Antibodies with Reflex to Confirmation

HTLV I/II Western Blot , ARUP# 51164, EPIC: LAB6059, SOFT: XHTLV

Instructions

Patients with positive results by ELISA will reflex to confirmation by Western Blot.

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube, Lavender-top EDTA tube, Green-top Sodium or Lithium Heparin tube, or Light Blue-top Sodium Citrate tube.

Send specimen for processing immediately after collection.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F) immediately.

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.

Storage

Ambient: 7 days (acceptable but not preferred)
Refrigerated: 7 days
Frozen: Indefinitely (avoid repeated freeze/thaw cycles)

Performed

Monday, Wednesday, Friday.
Results available in 2-6 days.

Reference Range

Negative.

Test Methodology

Qualitative Enzyme-Linked Immunosorbent Assay/Qualitative Western Blot.

Interpretation

ARUP intends use of this assay for clinical diagnosis. This assay should not be considered for blood donor screening or associated re-entry protocols.

Clinical Disease

Human T-Cell Lymphotropic Virus-1 (HTLV-1) has been associated with adult T-cell leukemia (ATL) and may play an indirect role in the pathocenesis of some B-cell chronic lymphocytic leukemia (CLL) cases. HTLV-1 has also been associated with chronic neurologic diseases including tropical spastic paraparesis (TSP) and HTLV-associated myelopathy (HAM). (1)

Reference

  1. Wiedbrauk D, Johnston SLG. Manual of Clinical Virology, Raven Press, New York, NY, 1993.

CPT Code

86790, (86689 if indicated for confirmation).

Test Codes

ARUP# 51164, EPIC: LAB6059, SOFT: XHTLV

Last Updated

7/11/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.